viral RNA synthesis, origin, and vaccines

In a recent study published in Current Research in Immunologyresearchers analyzed the characteristics of coronaviruses (CoVs) and novel CoV vaccine candidates. Study: Nature of viruses and pandemics: Coronaviruses. Image Credit: 3DJustincase/Shutterstock Background CoVs are a group of positive-strand, enveloped ribonucleic acid (RNA) viruses belonging to the Nidovirales order. There are four genera within the Orthocoronavirinae … Read more

“Selfish Genetic Elements” – Supergene Wreaks Havoc in a Genome

Rochester researchers used fruit flies as model organisms to study Segregator Distorter (SD), a selfish genetic element that skews the rules of fair genetic transmission. Credit: University of Rochester photo / J. Adam Fenster Biologists from University of Rochester used population genomics to study a selfish ‘supergene’ that skews genetic inheritance. “Selfish genetic elements” litter … Read more

From Cloning Monkeypox Genome to Editing Human DNA, Is Synthetic Biology a Double-Edged Sword?

In the June 2022 issue of Virologica Sinica, researchers at Wuhan Institute of Virology (WIV) published a paper that said WIV efficiently assembled a large fragment of the monkeypox virus genome for the purpose of developing a PCR test for monkeypox. This WIV article is not particularly eye-catching at first glance, but it does raise … Read more

Scientists expand entomological research using genome editing

Genome sequencing, where scientists use laboratory methods to determine a specific organism’s genetic makeup, is becoming a common practice in insect research. A greater understanding of insect biology helps scientists better manage insects, both those that are beneficial to the ecosystem and those that damage the food supply and threaten human health by carrying diseases. … Read more

‘Gold mine of unexplored biology’: Short protein sequences could dramatically expand human genome | Science

The relatively small universe of human genes could grow by up to one-third, if a concerted effort to search for new genes that encode short proteins is successful. Many known miniproteins have already been shown to play key roles in cellular metabolism and disease, so the international effort to catalog new ones and determine their … Read more

Biological E. to invest ₹1,800 crore in Hyderabad’s Genome Valley

Vaccine maker Biological E. will be investing ₹ 1,800 crore on expansion projects at three of its facilities in Genome Valley, Hyderabad. It is primarily to ramp up manufacturing of vaccines along with generic injectables and research and development (R&D), the office of Industries and IT Minister KT Rama Rao said on Thursday. Booster for … Read more

Gonorrhea bacteria may have driven the evolution of gene variants that protect older adults against dementia

Researchers at the University of California San Diego School of Medicine previously found a set of human gene mutations that protect older adults against cognitive decline and dementia. In a new study, published July 9, 2022 in Molecular Biology and Evolution, they focus on one of these mutated genes and attempt to trace its evolution … Read more

The Bizarre Bird That’s Breaking the Tree of Life

When Josefin Stiller was growing up in Berlin, she loved reading about Greek gods in an encyclopedia of mythology. She often lost track of their relationships, however — their feuds, trysts, and betrayals — as she flipped among the entries. Frustrated, she wrote each name on a card and started to arrange children beneath parents … Read more

Salk Research Professor Todd Michael receives $2 million to build a genome repository for the cassava plant – BIOENGINEER.ORG

LA JOLLA–– (July 1, 2022) Research Professor Todd Michael will receive nearly $ 2 million from the Bill & Melinda Gates Foundation to sequence the genomes of multiple lineages of the cassava plant, a large starchy root vegetable also known as yuca root consumed in more than 80 countries around the world. A better understanding … Read more

Biologists shed light on the evolution and consequences of selfish genetic elements

The human genome is littered with “selfish genetic elements,” which do not seem to benefit their hosts, but instead seek only to propagate themselves. Selfish genetic elements can wreak havoc by, for instance, distorting sex ratios, impairing fertility, causing harmful mutations, and even potentially causing population extinction. Biologists at the University of Rochester, including Amanda … Read more